disease of anatomical entity
Details about this human disease
Synonyms (0)None defined
Definitions (1)
A disease that manifests in a defined anatomical structure.
Related items
The study employed high quality non-mydriatic (i.e. pupil dilation is not required) fundus photography (FP) (Oculus Nidek AFC-230, 45 FOV) and a infra-red reflectance (IR) en face image obtained by scanning laser ophthalmoscope (SLO) (Heidelberg Spectralis, 30 FOV) to produce representative images of the retina and optic nerve. In order to prove the scale invariance property of tortuosity metrics, ophthalmological photographs from 18 subjects, both eyes, were randomly extracted from the ...
Programme: Default Programme
Public web page: https://turing.iimas.unam.mx/scaletort/
Coordinating investigators Prof. Dr. Jan C. Simon Prof. Dr. Regina Treudler Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Leipzig
Sponsor Universität Leipzig Ritterstr. 26, 04109 Leipzig
EudraCT: 2009-011737-27
Programme: University Leipzig (Sponsor)
Public web page: Not specified
LIFE Child wants to find out how environmental factors and lifestyles can affect the health of children and adolescents. The aim of the study is to examine civilization diseases such as allergies, obesity, diabetes, cardiovascular diseases in more detail. Furthermore, the study also focuses on healthy mental and physical development from the infant to the young adult. The team of the LIFE Child study around Prof. Dr. med. Wieland Kiess would like to examine and question about 5,000 subjects aged ...
Programme: LIFE Management Cluster
Public web page: http://www.life-child.de/
Start date: 1st Jan 2009
Historic retinal images of subjects with diabetes are scanned and analysed using modern technology. The accuracy of the methods and the usefulness of the findings in the long-term are in the focus. University of Oulu, Department of Ophthalmology/PEDEGO Research Unit 194/2006
Programme: This Project is not associated with a Programme
Public web page: https://www.oulu.fi/mrc/research-groups/falck-hautala
The LIFE-Heart study recruited 7,000 patients with suspected coronary heart disease, manifest heart disease or myocardial infarction. All patients received coronary angiography so that the vascular status in the heart is precisely known. In principle, this examination is not feasible in population-related studies. In addition, the patients were thoroughly examined with regard to the general vascular status and the health of the cardiovascular system. Extensive environmental factors were recorded. ...
Programme: LIFE Management Cluster
Public web page: http://life.uni-leipzig.de/
Start date: 1st Jan 2009
Goal of the Leipzig Research Center for Civilization Diseases (LIFE) is the investigation of civilization diseases like depression, diabetes, allergies or cardiovascular diseases. For this purpose we collect as much data as possible regarding health and living conditions of the population in Leipzig and provide these data for scientists of the University of Leipzig and other research institutions.
Programme: LIFE Management Cluster
Public web page: http://life.uni-leipzig.de/
Start date: 1st Jan 2009
This population-based study examined 10,000 participants randomly selected from the Leipzig population (2011 to 2014). A follow-up is to be carried out from 2017 - 2020. The study mainly included people aged between 40 and 79. All participants underwent a 6-hour study program and people over 60 years of age were invited two more times to in-depth study of cognition and depression and the brain (MRI, EEG). Extensive measurements of genome, metabolome and transcriptome are available. The LIFE-ADULT ...
Programme: LIFE Management Cluster
Public web page: http://life.uni-leipzig.de/en/adults/life_adult.html
Start date: 1st Jan 2009
The aim of this project is to validate and improve an in vitro test system developed in a previous project for the prediction of hepatotoxicity induced by chemical substances and drugs. For this purpose, the test system will be supplemented with immunological cells in order to be able to detect idiosyncratic reactions. In the subproject of the working group of Prof. Daniel Seehofer and Dr. Georg Damm, primary liver cells will be provided and the in vitro model will be improved by Kupffer cells.
Programme: This Project is not associated with a Programme
Public web page: Not specified
Start date: 1st Feb 2017
End date: 31st Dec 2020
CAPSyS is an interdisciplinary research network that investigates the causes and course of severe pneumonia. The network works in five subprojects at seven locations throughout Germany. CAPSyS is funded by the Federal Ministry of Education and Research (BMBF) with 3.8 million euros.
Programme: This Project is not associated with a Programme
Public web page: https://www.capsys.imise.uni-leipzig.de
Start date: 1st Jan 2014
End date: 1st Jan 2019
Programme: This Project is not associated with a Programme
Public web page: Not specified
Example study for people with hypertension or obesity as inclusion criteria. This ontology uses the Core Ontology of Phenotypes as a general phenotypic model.
Submitter: Christoph Beger
Biological problem addressed: Model Analysis Type
Investigation: Phenotype Knowledge Model
We are releasing the summary data from our GWAMA of PCSK9 levels, pending on acceptance of our publication, to empower other researchers to examine variants or loci in which they are interested for associations. These data are intended for research purposes only.
Citation: tba
When using this data acknowledge the source as follows: 'Data on PCSK9 has been downloaded from https://www.health-atlas.de/data_files/551.'
For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) ...
Submitter: Janne Pott
Resource type: Experimental Assay Type
Technology type: SNP Array
Investigation: OMICS Investigations
Study: GWAMA PCSK9
We are releasing the summary data from our GWAS of carotid plaque burden traits, pending on acceptance of our publication, to empower other researchers to examine variants or loci in which they are interested for associations. These data are intended for research purposes only.
Citation:
When using this data acknowledge the source as follows: 'Data on carotid plaque burden has been contributed by LIFE-Adult investigators and has been downloaded from https://www.health-atlas.de/assays/31 '
For any ...
Submitter: Janne Pott
Resource type: Genome Wide Association
Technology type: SNP Array
Investigation: OMICS Investigations
Study: GWAS Carotid Plaque Burden
This assay bundles all synthetic FHIR data of the PhenoMan evaluation. The data arised from a subset of a Synthea(TM) generated data set. We truncated some resource types like Encounter and Provider to reduce the size of the data set and to speed up the import in a FHIR health data store.
Submitter: Christoph Beger
Resource type: Result Dataset of Clinical Study
Technology type: Technology Type
Investigation: Ontology-based Phenotyping
The primary goal of this study was to identify genetic loci associated with steroid hormone levels (cortisol, DHEA-S, testosterone, estradiol, progesterone, 17-hydroxyprogesterone, androstenedione, and aldosterone). In a secondary analysis, we searched for causal effects of steroid hormones on coronary artery disease.
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Investigation: OMICS Investigations
Study: GWAS Steroid Hormones
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival) Sample Size: 189
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Investigation: SMARTE-R-CHOP-14
Study: SMARTE-R-CHOP-14
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival) Sample Size: 189
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Investigation: SMARTE-R-CHOP-14
Study: SMARTE-R-CHOP-14
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival) Sample Size: 268
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Investigation: SEXIE-R-CHOP-14
Study: SEXIE-R-CHOP-14
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival) Sample Size: 268
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Investigation: SEXIE-R-CHOP-14
Study: SEXIE-R-CHOP-14
Demographics, reference pathology diagnosis, Outcome (Event-free survival, Progression-free survival, Overall survival)
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Investigation: RICOVER-noRTh
Study: RICOVER-noRTh
Abstract (Expand)
Authors: Andrea Zimmermann, René Hänsel, Kilian Gemünden, Victoria Kegel-Hübner, Jonas Babel, Hendrik Bläker, Madlen Matz-Soja, Daniel Seehofer, Georg Damm
Date Published: 1st Apr 2021
Publication Type: Journal article
Human Diseases: liver disease, liver cancer
Abstract (Expand)
Authors: Nasim Mavaddat, Antonis C. Antoniou, Thea M. Mooij, Maartje J. Hooning, Bernadette A. Heemskerk-Gerritsen, Catherine Noguès, Marion Gauthier-Villars, Olivier Caron, Paul Gesta, Pascal Pujol, Alain Lortholary, Daniel Barrowdale, Debra Frost, D. Gareth Evans, Louise Izatt, Julian Adlard, Ros Eeles, Carole Brewer, Marc Tischkowitz, Alex Henderson, Jackie Cook, Diana Eccles, Klaartje van Engelen, Marian J. E. Mourits, Margreet G. E. M. Ausems, Linetta B. Koppert, John L. Hopper, Esther M. John, Wendy K. Chung, Irene L. Andrulis, Mary B. Daly, Saundra S. Buys, Javier Benitez, Trinidad Caldes, Anna Jakubowska, Jacques Simard, Christian F. Singer, Yen Tan, Edith Olah, Marie Navratilova, Lenka Foretova, Anne-Marie Gerdes, Marie-José Roos-Blom, Flora E. van Leeuwen, Brita Arver, Håkan Olsson, Rita K. Schmutzler, Christoph Engel, Karin Kast, Kelly-Anne Phillips, Mary Beth Terry, Roger L. Milne, David E. Goldgar, Matti A. Rookus, Nadine Andrieu, Douglas F. Easton
Date Published: 1st Dec 2020
Publication Type: Journal article
Human Diseases: hereditary breast ovarian cancer syndrome
Abstract
Authors: Nasim Mavaddat, Antonis C. Antoniou, Thea M. Mooij, Maartje J. Hooning, Bernadette A. Heemskerk-Gerritsen, Catherine Noguès, Marion Gauthier-Villars, Olivier Caron, Paul Gesta, Pascal Pujol, Alain Lortholary, Daniel Barrowdale, Debra Frost, D. Gareth Evans, Louise Izatt, Julian Adlard, Ros Eeles, Carole Brewer, Marc Tischkowitz, Alex Henderson, Jackie Cook, Diana Eccles, Klaartje van Engelen, Marian J. E. Mourits, Margreet G. E. M. Ausems, Linetta B. Koppert, John L. Hopper, Esther M. John, Wendy K. Chung, Irene L. Andrulis, Mary B. Daly, Saundra S. Buys, Javier Benitez, Trinidad Caldes, Anna Jakubowska, Jacques Simard, Christian F. Singer, Yen Tan, Edith Olah, Marie Navratilova, Lenka Foretova, Anne-Marie Gerdes, Marie-José Roos-Blom, Flora E. van Leeuwen, Brita Arver, Håkan Olsson, Rita K. Schmutzler, Christoph Engel, Karin Kast, Kelly-Anne Phillips, Mary Beth Terry, Roger L. Milne, David E. Goldgar, Matti A. Rookus, Nadine Andrieu, Douglas F. Easton
Date Published: 1st Dec 2020
Publication Type: Journal article
Human Diseases: hereditary breast ovarian cancer syndrome
Abstract (Expand)
Authors: Michael Rode, Andrej Teren, Kerstin Wirkner, Katrin Horn, Holger Kirsten, Markus Loeffler, Markus Scholz, Janne Pott
Date Published: 13th Aug 2020
Publication Type: Journal article
Human Diseases: arteriosclerosis, arteriosclerotic cardiovascular disease
Abstract (Expand)
Authors: Valentina Silvestri, Goska Leslie, Daniel R. Barnes, Bjarni A. Agnarsson, Kristiina Aittomäki, Elisa Alducci, Irene L. Andrulis, Rosa B. Barkardottir, Alicia Barroso, Daniel Barrowdale, Javier Benitez, Bernardo Bonanni, Ake Borg, Saundra S. Buys, Trinidad Caldés, Maria A. Caligo, Carlo Capalbo, Ian Campbell, Wendy K. Chung, Kathleen B. M. Claes, Sarah V. Colonna, Laura Cortesi, Fergus J. Couch, Miguel de La Hoya, Orland Diez, Yuan Chun Ding, Susan Domchek, Douglas F. Easton, Bent Ejlertsen, Christoph Engel, D. Gareth Evans, Lidia Feliubadalò, Lenka Foretova, Florentia Fostira, Lajos Géczi, Anne-Marie Gerdes, Gord Glendon, Andrew K. Godwin, David E. Goldgar, Eric Hahnen, Frans B. L. Hogervorst, John L. Hopper, Peter J. Hulick, Claudine Isaacs, Angel Izquierdo, Paul A. James, Ramunas Janavicius, Uffe Birk Jensen, Esther M. John, Vijai Joseph, Irene Konstantopoulou, Allison W. Kurian, Ava Kwong, Elisabetta Landucci, Fabienne Lesueur, Jennifer T. Loud, Eva Machackova, Phuong L. Mai, Keivan Majidzadeh-A, Siranoush Manoukian, Marco Montagna, Lidia Moserle, Anna Marie Mulligan, Katherine L. Nathanson, Heli Nevanlinna, Joanne Ngeow Yuen Ye, Liene Nikitina-Zake, Kenneth Offit, Edith Olah, Olufunmilayo I. Olopade, Ana Osorio, Laura Papi, Sue K. Park, Inge Sokilde Pedersen, Pedro Perez-Segura, Annabeth H. Petersen, Pedro Pinto, Berardino Porfirio, Miquel Angel Pujana, Paolo Radice, Johanna Rantala, Muhammad U. Rashid, Barak Rosenzweig, Maria Rossing, Marta Santamariña, Rita K. Schmutzler, Leigha Senter, Jacques Simard, Christian F. Singer, Angela R. Solano, Melissa C. Southey, Linda Steele, Zoe Steinsnyder, Dominique Stoppa-Lyonnet, Yen Yen Tan, Manuel R. Teixeira, Soo H. Teo, Mary Beth Terry, Mads Thomassen, Amanda E. Toland, Sara Torres-Esquius, Nadine Tung, Christi J. van Asperen, Ana Vega, Alessandra Viel, Jeroen Vierstraete, Barbara Wappenschmidt, Jeffrey N. Weitzel, Greet Wieme, Sook-Yee Yoon, Kristin K. Zorn, Lesley McGuffog, Michael T. Parsons, Ute Hamann, Mark H. Greene, Judy A. Kirk, Susan L. Neuhausen, Timothy R. Rebbeck, Marc Tischkowitz, Georgia Chenevix-Trench, Antonis C. Antoniou, Eitan Friedman, Laura Ottini
Date Published: 2nd Jul 2020
Publication Type: Journal article
Human Diseases: hereditary breast ovarian cancer syndrome
Abstract (Expand)
Authors: Helian Feng, Alexander Gusev, Bogdan Pasaniuc, Lang Wu, Jirong Long, Zomoroda Abu-Full, Kristiina Aittomäki, Irene L. Andrulis, Hoda Anton-Culver, Antonis C. Antoniou, Adalgeir Arason, Volker Arndt, Kristan J. Aronson, Banu K. Arun, Ella Asseryanis, Paul L. Auer, Jacopo Azzollini, Judith Balmaña, Rosa B. Barkardottir, Daniel R. Barnes, Daniel Barrowdale, Matthias W. Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Katarzyna Białkowska, Ana Blanco, Carl Blomqvist, Bram Boeckx, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Bernardo Bonanni, Ake Borg, Hiltrud Brauch, Hermann Brenner, Ignacio Briceno, Annegien Broeks, Thomas Brüning, Barbara Burwinkel, Qiuyin Cai, Trinidad Caldés, Maria A. Caligo, Ian Campbell, Sander Canisius, Daniele Campa, Brian D. Carter, Jonathan Carter, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Hans Christiansen, Wendy K. Chung, Kathleen B. M. Claes, Christine L. Clarke, Fergus J. Couch, Angela Cox, Simon S. Cross, Cezary Cybulski, Kamila Czene, Mary B. Daly, Miguel de La Hoya, Kim de Leeneer, Joe Dennis, Peter Devilee, Orland Diez, Susan M. Domchek, Thilo Dörk, Isabel Dos-Santos-Silva, Alison M. Dunning, Miriam Dwek, Diana M. Eccles, Bent Ejlertsen, Carolina Ellberg, Christoph Engel, Mikael Eriksson, Peter A. Fasching, Olivia Fletcher, Henrik Flyger, Florentia Fostira, Eitan Friedman, Lin Fritschi, Debra Frost, Marike Gabrielson, Patricia A. Ganz, Susan M. Gapstur, Judy Garber, Montserrat García-Closas, José A. García-Sáenz, Mia M. Gaudet, Graham G. Giles, Gord Glendon, Andrew K. Godwin, Mark S. Goldberg, David E. Goldgar, Anna González-Neira, Mark H. Greene, Jacek Gronwald, Pascal Guénel, Christopher A. Haiman, Per Hall, Ute Hamann, Christopher Hake, Wei He, Jane Heyworth, Frans B. L. Hogervorst, Antoinette Hollestelle, Maartje J. Hooning, Robert N. Hoover, John L. Hopper, Guanmengqian Huang, Peter J. Hulick, Keith Humphreys, Evgeny N. Imyanitov, Claudine Isaacs, Milena Jakimovska, Anna Jakubowska, Paul James, Ramunas Janavicius, Rachel C. Jankowitz, Esther M. John, Nichola Johnson, Vijai Joseph, Audrey Jung, Beth Y. Karlan, Elza Khusnutdinova, Johanna I. Kiiski, Irene Konstantopoulou, Vessela N. Kristensen, Yael Laitman, Diether Lambrechts, Conxi Lazaro, Dominique Leroux, Goska Leslie, Jenny Lester, Fabienne Lesueur, Noralane Lindor, Sara Lindström, Wing-Yee Lo, Jennifer T. Loud, Jan Lubiński, Enes Makalic, Arto Mannermaa, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, John W. M. Martens, Maria E. Martinez, Laura Matricardi, Tabea Maurer, Dimitrios Mavroudis, Lesley McGuffog, Alfons Meindl, Usha Menon, Kyriaki Michailidou, Pooja M. Kapoor, Austin Miller, Marco Montagna, Fernando Moreno, Lidia Moserle, Anna M. Mulligan, Taru A. Muranen, Katherine L. Nathanson, Susan L. Neuhausen, Heli Nevanlinna, Ines Nevelsteen, Finn C. Nielsen, Liene Nikitina-Zake, Kenneth Offit, Edith Olah, Olufunmilayo I. Olopade, Håkan Olsson, Ana Osorio, Janos Papp, Tjoung-Won Park-Simon, Michael T. Parsons, Inge S. Pedersen, Ana Peixoto, Paolo Peterlongo, Julian Peto, Paul D. P. Pharoah, Kelly-Anne Phillips, Dijana Plaseska-Karanfilska, Bruce Poppe, Nisha Pradhan, Karolina Prajzendanc, Nadege Presneau, Kevin Punie, Katri Pylkäs, Paolo Radice, Johanna Rantala, Muhammad Usman Rashid, Gad Rennert, Harvey A. Risch, Mark Robson, Atocha Romero, Emmanouil Saloustros, Dale P. Sandler, Catarina Santos, Elinor J. Sawyer, Marjanka K. Schmidt, Daniel F. Schmidt, Rita K. Schmutzler, Minouk J. Schoemaker, Rodney J. Scott, Priyanka Sharma, Xiao-Ou Shu, Jacques Simard, Christian F. Singer, Anne-Bine Skytte, Penny Soucy, Melissa C. Southey, John J. Spinelli, Amanda B. Spurdle, Jennifer Stone, Anthony J. Swerdlow, William J. Tapper, Jack A. Taylor, Manuel R. Teixeira, Mary Beth Terry, Alex Teulé, Mads Thomassen, Kathrin Thöne, Darcy L. Thull, Marc Tischkowitz, Amanda E. Toland, Rob A. E. M. Tollenaar, Diana Torres, Thérèse Truong, Nadine Tung, Celine M. Vachon, Christi J. van Asperen, Ans M. W. van den Ouweland, Elizabeth J. van Rensburg, Ana Vega, Alessandra Viel, Paula Vieiro-Balo, Qin Wang, Barbara Wappenschmidt, Clarice R. Weinberg, Jeffrey N. Weitzel, Camilla Wendt, Robert Winqvist, Xiaohong R. Yang, Drakoulis Yannoukakos, Argyrios Ziogas, Roger L. Milne, Douglas F. Easton, Georgia Chenevix-Trench, Wei Zheng, Peter Kraft, Xia Jiang
Abstract (Expand)
Authors: J. Pott, F. Beutner, K. Horn, H. Kirsten, K. Olischer, K. Wirkner, M. Loeffler, M. Scholz
Date Published: 30th May 2020
Publication Type: Journal article
Human Diseases: cardiovascular system disease, atherosclerosis
Abstract (Expand)
Authors: G. G. Wulf, B. Altmann, M. Ziepert, F. D'Amore, G. Held, R. Greil, O. Tournilhac, T. Relander, A. Viardot, M. Wilhelm, C. Wilhelm, A. Pezzutto, J. M. Zijlstra, E. V. D. Neste, P. J. Lugtenburg, J. K. Doorduijn, M. V. Gelder, G. W. van Imhoff, F. Zettl, F. Braulke, M. Nickelsen, B. Glass, A. Rosenwald, P. Gaulard, M. Loeffler, M. Pfreundschuh, N. Schmitz, L. Trumper
Date Published: 10th May 2020
Publication Type: Journal article
Human Diseases: lymphoma, peripheral T-cell lymphoma
Abstract (Expand)
Authors: Marcus Wagner, Sarah Reinke, René Hänsel, Wolfram Klapper, Ulf-Dietrich Braumann
Date Published: 12th Mar 2020
Publication Type: Journal article
Human Diseases: diffuse large B-cell lymphoma
Abstract (Expand)
Authors: Xin Yang, Goska Leslie, Alicja Doroszuk, Sandra Schneider, Jamie Allen, Brennan Decker, Alison M. Dunning, James Redman, James Scarth, Inga Plaskocinska, Craig Luccarini, Mitul Shah, Karen Pooley, Leila Dorling, Andrew Lee, Muriel A. Adank, Julian Adlard, Kristiina Aittomäki, Irene L. Andrulis, Peter Ang, Julian Barwell, Jonine L. Bernstein, Kristie Bobolis, Åke Borg, Carl Blomqvist, Kathleen B. M. Claes, Patrick Concannon, Adeline Cuggia, Julie O. Culver, Francesca Damiola, Antoine de Pauw, Orland Diez, Jill S. Dolinsky, Susan M. Domchek, Christoph Engel, D. Gareth Evans, Florentia Fostira, Judy Garber, Lisa Golmard, Ellen L. Goode, Stephen B. Gruber, Eric Hahnen, Christopher Hake, Tuomas Heikkinen, Judith E. Hurley, Ramunas Janavicius, Zdenek Kleibl, Petra Kleiblova, Irene Konstantopoulou, Anders Kvist, Holly Laduca, Ann S. G. Lee, Fabienne Lesueur, Eamonn R. Maher, Arto Mannermaa, Siranoush Manoukian, Rachel McFarland, Wendy McKinnon, Alfons Meindl, Kelly Metcalfe, Nur Aishah Mohd Taib, Jukka Moilanen, Katherine L. Nathanson, Susan Neuhausen, Pei Sze Ng, Tu Nguyen-Dumont, Sarah M. Nielsen, Florian Obermair, Kenneth Offit, Olufunmilayo I. Olopade, Laura Ottini, Judith Penkert, Katri Pylkäs, Paolo Radice, Susan J. Ramus, Vilius Rudaitis, Lucy Side, Rachel Silva-Smith, Valentina Silvestri, Anne-Bine Skytte, Thomas Slavin, Jana Soukupova, Carlo Tondini, Alison H. Trainer, Gary Unzeitig, Lydia Usha, Thomas van Overeem Hansen, James Whitworth, Marie Wood, Cheng Har Yip, Sook-Yee Yoon, Amal Yussuf, George Zogopoulos, David Goldgar, John L. Hopper, Georgia Chenevix-Trench, Paul Pharoah, Sophia H. L. George, Judith Balmaña, Claude Houdayer, Paul James, Zaki El-Haffaf, Hans Ehrencrona, Marketa Janatova, Paolo Peterlongo, Heli Nevanlinna, Rita Schmutzler, Soo-Hwang Teo, Mark Robson, Tuya Pal, Fergus Couch, Jeffrey N. Weitzel, Aaron Elliott, Melissa Southey, Robert Winqvist, Douglas F. Easton, William D. Foulkes, Antonis C. Antoniou, Marc Tischkowitz
Date Published: 1st Mar 2020
Publication Type: Journal article
Human Diseases: hereditary breast ovarian cancer syndrome
SCALE-TORT database contains a total of 226 FP/IR paired arterial vessel curves and 245 FP/IR paired vein vessel curves, all 471 paried curves where semiautomatically extracted from the original images.
- Folder 'im_arteries' with: 1.1 226 croped images from FP of retinal arteries 1.2 226 croped images from IR of retinal arteries
- Folder 'im_veins' with: 2.1. 245 croped images from FP of retinal veins 2.2. 245 croped images from IR of retinal veins
- Matlab structure for arteries annotations ...
Creators: None
Submitter: Zian Fanti Gutiérrez
Data file type: Clinical Data
Human Diseases: hypertension
Download
Creators: Alexandr Uciteli, Christoph Beger, Toralf Kirsten, Heinrich Herre, Franz Matthies, Ralph Schäfermeier
Submitter: Christoph Beger
Data file type: Not specified
Human Diseases: obesity, hypertension
Creator: René Hänsel
Submitter: René Hänsel
Data file type: Clinical Data
Human Diseases: peripheral T-cell lymphoma
Creator: René Hänsel
Submitter: René Hänsel
Data file type: ODM Data
Human Diseases: peripheral T-cell lymphoma
Creator: René Hänsel
Submitter: René Hänsel
Data file type: Clinical Data
Human Diseases: peripheral T-cell lymphoma
Summary statistics from GWAMA of PCSK9 levels. These data are intended for research purposes only, and available upon publication. For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) or Markus Scholz (markus.scholz@imise.uni-leipzig.de).
Citation: tba
When using this data acknowledge the source as follows: 'Data on PCSK9 has been downloaded from https://www.health-atlas.de/data_files/551'
We make three data sets available:
- Containing statistics ...
Creator: Janne Pott
Submitter: Janne Pott
Data file type: Not specified
Human Diseases: atherosclerosis
We performed gene-expression profiling using Affymetrix U133A GeneChips with RNA from 220 mature aggressive B-cell lymphomas, including a core group of 8 Burkitt's lymphomas that met all World Health Organization (WHO) criteria. A molecular signature for Burkitt's lymphoma was generated, and chromosomal abnormalities were detected with interphase fluorescence in situ hybridization and array-based comparative genomic hybridization.
Creator: Michael Hummel
Submitter: Christoph Beger
Data file type: Genomic Data
Human Diseases: B-cell lymphoma
The 'Future 10-year risk calculator' is a tool designed to help determine the optimal timing for follow-up counseling based on the cumulative breast cancer risks provided in the CanRisk-Report created by the CanRisk website as a result of the BOADICEA risk assessment. It is not a replacement for the BOADICEA model, nor is it intended for medical diagnosis, treatment decisions, or the monitoring of health conditions. The risk estimation assumes that the individual's and family's risk profile remains ...
Creators: Christoph Engel, Silke Zachariae
Submitter: Silke Zachariae
Model type: Not specified
Model format: R package
Environment: Shiny
Introduction On this homepage we provide a web-based tool to calculate prognostic scores on haematopoietic toxicity for 6 cycles CHOP-like regimen in patients with aggressive NHL. As we used for this analysis the data collected within the NHL-B1 and NHL-B2 trials of the DSHNHL as described in detail in Pfreundschuh et al. the predictions are valid for similar patient populations.
Description We offer two types of models. Pre-treatment models include beside the therapy regimen only prognostic ...
Creator: Marita Ziepert
Submitter: René Hänsel
Model type: Not specified
Model format: Not specified
Environment: Not specified
External LinkImplementation of recently developed dynamic mathematical models of normal and leukemic hematopoiesis to practically impact clinical decision- making.
Fitting available individual patients information, prediction of next-cycle thrombopenia caused by CHOEP treatment based on the individual fits of the preceeding treatment cycles, changing next-cycle relative dosing, posponement of the next cycle, changing follow-up period, visualization of data and simulation
Creator: Markus Scholz
Submitter: René Hänsel
Model type: Not specified
Model format: R package
Environment: Not specified
This is an interactive version of figure 4 of the publication „Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood“.
Creator: Markus Scholz
Submitter: René Hänsel
Model type: Not specified
Model format: R package
Environment: Not specified
Creator: Thomas Peschel
Submitter: Thomas Peschel
Model type: Not specified
Model format: R package
Environment: Not specified
This Shiny-App implements the calculation of several CAP (Community-Aquired-Pneumonia) severity scores for one or multiple patients based on user-updated data.
Creators: Markus Scholz, Maciej Rosolowski, Carl Beuchel
Submitter: Carl Beuchel
Model type: Algebraic equations
Model format: R package
Environment: Shiny
View contentDepending on the calculated mutation probability genetic counsellors can decide whether patients should undergo further analysis of microsatellite instability and immunohistochemistry. The model is recommended for patients with an age at colorectal cancer diagnosis of 55 or younger.
"MMRpredict" is a risk prediction model for patients with colorectal cancer (Barnetson et al. 2006). It calculates the risk of having a mutation in the mismatch repair genes MLH1, MSH2 and MSH6 (overall probability) ...
Creators: Christoph Engel, Silke Zachariae
Submitter: Silke Zachariae
Model type: Not specified
Model format: R package
Environment: Shiny
The PREMM1,2,6 has been developed as a pretest to decide whether patients suspected of having Lynch syndrome should be tested for germline mismatch repair gene mutations. "PREMM1,2,6" is a logistic regression model. It calculates the risk of having a mutation in the mismatch repair genes MLH1, MSH2 and MSH6 (for single genes and overall) based on the personal and familial cancer history of the proband (colorectal, endometrial, and other Lynch syndrome related cancers).
Creators: Silke Zachariae, Christoph Engel, Kastrinos et al.
Submitter: Silke Zachariae
Model type: Not specified
Model format: R package
Environment: Shiny
Motivation: The "Manchester Scoring System" can be used to assist clinicians and genetic counselors in the clinical management of families suspected of having hereditary breast and ovarian cancer and to decide whether genetic testing should be performed.
Description: The "Manchester Scoring System" is an empirical mutation risk prediction model. In its current form, a risk score for the identification of a pathogenic BRCA1/2 mutation is being calculated based on the number of breast and ovarian ...
Creators: Christoph Engel, Silke Zachariae, Evans, D.G. et al. (2009)
Submitter: Silke Zachariae
Model type: Not specified
Model format: R package
Environment: Shiny
The GC-HBOC BC Risk Explorer (GC-HBOC BC-RE) predicts the breast cancer risk for BRCA1/2 carriers and high-risk non-carriers at risk for first breast cancer (cohort 1), and BRCA1/2 carriers and high-risk non-carriers who were previously diagnosed with unilateral breast cancer, and are at risk for contralateral breast cancer (cohort 2). GC-HBOC BC-RE is based on data from female BRCA1/2 carriers and non-carriers with a family history of breast and ovarian cancer, who participated in the intensified ...
Creators: Christoph Engel, Silke Zachariae
Submitter: Silke Zachariae
Model type: Not specified
Model format: R package
Environment: Shiny
