We are releasing the summary data from our GWAMA of phytosterol traits, pending on acceptance of our publication, to empower other researchers to examine variants or loci in which they are interested for associations. These data are intended for research purposes only.
Citation: tba
When using this data acknowledge the source as follows: 'Data on phytosterol X has been contributed by LIFE investigators and has been downloaded from https://www.health-atlas.de/assays/53.'
For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) or Markus Scholz (markus.scholz@imise.uni-leipzig.de)
For each of the four analyzed phytosterols, we make two data sets available:
- Containing statistics regarding the analyses of free, esterified, free to esterified ratio, and total phytosterol level.
- Containing statistics regarding the analyses of the phytosterol to cholesterol and phytosterol to lanosterol ratios.
Files are in text delimited format and include:
- markername
- chr
- bp (base position according to hg19)
- ea (effect allele)
- oa (other allele)
- eaf (weighted effect allele frequency)
- info (minimal info score across all used studies)
- nSamples
- nStudies
- beta
- se
- p
- I²
LHA ID: 87NWD6QP27-8
Experimental assay
Projects: Genetical Statistics and Systems Biology, LIFE Adult, LIFE Heart
Investigation: OMICS Investigations
Study: GWAMA Phytosterole
Assay position:
Resource type: Experimental Assay Type
Technology type: SNP Array
Human Diseases: No human diseases
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Created: 1st Jul 2021 at 12:00
Last updated: 1st Jul 2021 at 16:02
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Programme: LIFE Management Cluster
Public web page: http://life.uni-leipzig.de/
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Organisms: Homo sapiens
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Goal of the Leipzig Research Center for Civilization Diseases (LIFE) is the investigation of civilization diseases like depression, diabetes, allergies or cardiovascular diseases. For this purpose we collect as much data as possible regarding health and living conditions of the population in Leipzig and provide these data for scientists of the University of Leipzig and other research institutions.
Programme: LIFE Management Cluster
Public web page: http://life.uni-leipzig.de/
Start date: 1st Jan 2009
This population-based study examined 10,000 participants randomly selected from the Leipzig population (2011 to 2014). A follow-up is to be carried out from 2017 - 2020. The study mainly included people aged between 40 and 79. All participants underwent a 6-hour study program and people over 60 years of age were invited two more times to in-depth study of cognition and depression and the brain (MRI, EEG). Extensive measurements of genome, metabolome and transcriptome are available. The LIFE-ADULT ...
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Public web page: http://life.uni-leipzig.de/en/adults/life_adult.html
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Organisms: Homo sapiens
Human Diseases: mood disorder, dementia, coronary artery disease, obesity
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Programme: This Project is not associated with a Programme
Public web page: http://www.imise.uni-leipzig.de/en/Groups/GenStat/
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Resutls of different OMICS-level using LIFE Adult and LIFE Heart data are presented (Publications, Supplemental Data, & Summary Statistics).
Submitter: René Hänsel
Studies: DNA methylation patterns reflect individual lifestyle independent from o..., GWAMA PCSK9, GWAMA Phytosterole, GWAMA Steroid hormones, GWAMA vaspin, GWAS Body Scanner Measures, GWAS Carotid Plaque Burden, GWAS Pulse Wave Velocity, GWAS Steroid Hormones, scRNA-Seq across species for pulmonologists
Resources: Gene Expression data, LIFE-Adult EPIC data, Summary Statistic for PWV GWAS, Summary Statistics, Summary Statistics, Summary Statistics, Summary Statistics, Summary Statistics, Summary Statistics - Phytosterols, Supplement Data, scRNA-Seq expression data as RDS Seurat file
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Genome-wide Association Meta-Analyses of 32 phytosterol traits reflecting resorption, cholesterol synthesis and esterification in six studies with up to 9,758 subjects Summary statistics of GWAMA results will be made available upon acceptance of our manuscript.
Submitter: Janne Pott
Investigation: OMICS Investigations
Resources: Summary Statistics - Phytosterols
Study type: Genetic study
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Summary statistics from GWAMA of stigmasterol (stf_chf, free stigmasterol to free cholesterol; stt_cht, total stigmasterol to total cholesterol; stf_laf, free stigmasterol to free lanosterol; stt_laf, total stigmasterol to free lanosterol). These data are intended for research purposes only, and available upon publication. For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) or Markus Scholz (markus.scholz@imise.uni-leipzig.de).
Citation: tba
When ...
Creators: Katrin Horn, Markus Scholz, Janne Pott
Submitter: Janne Pott
Data file type: Other OMICs Data
Relationship type: Not specified
Investigations: OMICS Investigations
Studies: GWAMA Phytosterole
Resources: Summary Statistics - Phytosterols
Summary statistics from GWAMA of stigmasterol (ste, esterified stigmasterol; stf, free stigmasterol; stt, total stigmasterol; stf_ste, free to esterified stigmasterol). These data are intended for research purposes only, and available upon publication. For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) or Markus Scholz (markus.scholz@imise.uni-leipzig.de).
Citation: tba
When using this data acknowledge the source as follows: 'Data on stigmasterol ...
Creators: Katrin Horn, Markus Scholz, Janne Pott
Submitter: Janne Pott
Data file type: Other OMICs Data
Relationship type: Not specified
Investigations: OMICS Investigations
Studies: GWAMA Phytosterole
Resources: Summary Statistics - Phytosterols
Summary statistics from GWAMA of sitosterol (sif_chf, free sitosterol to free cholesterol; sit_cht, total sitosterol to total cholesterol; sif_laf, free sitosterol to free lanosterol; sit_laf, total sitosterol to free lanosterol). These data are intended for research purposes only, and available upon publication. For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) or Markus Scholz (markus.scholz@imise.uni-leipzig.de).
Citation: tba
When using this ...
Creators: Katrin Horn, Markus Scholz, Janne Pott
Submitter: Janne Pott
Data file type: Other OMICs Data
Relationship type: Not specified
Investigations: OMICS Investigations
Studies: GWAMA Phytosterole
Resources: Summary Statistics - Phytosterols
Summary statistics from GWAMA of sitosterol (sie, esterified sitosterol; sif, free sitosterol; sit, total sitosterol; sif_sie, free to esterified sitosterol). These data are intended for research purposes only, and available upon publication. For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) or Markus Scholz (markus.scholz@imise.uni-leipzig.de).
Citation: tba
When using this data acknowledge the source as follows: 'Data on sitosterol has been ...
Creators: Katrin Horn, Markus Scholz, Janne Pott
Submitter: Janne Pott
Data file type: Other OMICs Data
Relationship type: Not specified
Investigations: OMICS Investigations
Studies: GWAMA Phytosterole
Resources: Summary Statistics - Phytosterols
Summary statistics from GWAMA of campesterol (caf_chf, free campesterol to free cholesterol; cat_cht, total campesterol to total cholesterol; caf_laf, free campesterol to free lanosterol; cat_laf, total campesterol to free lanosterol). These data are intended for research purposes only, and available upon publication. For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) or Markus Scholz (markus.scholz@imise.uni-leipzig.de).
Citation: tba
When using ...
Creators: Katrin Horn, Markus Scholz, Janne Pott
Submitter: Janne Pott
Data file type: Other OMICs Data
Relationship type: Not specified
Investigations: OMICS Investigations
Studies: GWAMA Phytosterole
Resources: Summary Statistics - Phytosterols
Summary statistics from GWAMA of campesterol (cae, esterified campesterol; caf, free campesterol; cat, total campesterol; caf_cae, free to esterified campesterol). These data are intended for research purposes only, and available upon publication. For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) or Markus Scholz (markus.scholz@imise.uni-leipzig.de).
Citation: tba
When using this data acknowledge the source as follows: 'Data on campesterol has been ...
Creators: Katrin Horn, Markus Scholz, Janne Pott
Submitter: Janne Pott
Data file type: Other OMICs Data
Relationship type: Not specified
Investigations: OMICS Investigations
Studies: GWAMA Phytosterole
Resources: Summary Statistics - Phytosterols
Summary statistics from GWAMA of brassicasterol (brf_chf, free brassicasterol to free cholesterol; brt_cht, total brassicasterol to total cholesterol; brf_laf, free brassicasterol to free lanosterol; brt_laf, total brassicasterol to free lanosterol). These data are intended for research purposes only, and available upon publication. For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) or Markus Scholz (markus.scholz@imise.uni-leipzig.de).
Citation: ...
Creators: Katrin Horn, Markus Scholz, Janne Pott
Submitter: Janne Pott
Data file type: Other OMICs Data
Relationship type: Not specified
Investigations: OMICS Investigations
Studies: GWAMA Phytosterole
Resources: Summary Statistics - Phytosterols
Summary statistics from GWAMA of brassicasterol (bre, esterified brassicasterol; brf, free brassicasterol; brt, total brassicasterol; brf_bre, free to esterified brassicasterol). These data are intended for research purposes only, and available upon publication. For any enquiries about the datasets, please contact Janne Pott (janne.pott@imise.uni-leipzig.de) or Markus Scholz (markus.scholz@imise.uni-leipzig.de).
Citation: tba
When using this data acknowledge the source as follows: 'Data on ...
Creators: Katrin Horn, Markus Scholz, Janne Pott
Submitter: Janne Pott
Data file type: Other OMICs Data
Relationship type: Not specified
Investigations: OMICS Investigations
Studies: GWAMA Phytosterole
Resources: Summary Statistics - Phytosterols
Projects: LIFE Heart, LIFE - Leipzig Research Center for Civilization Diseases, HaematoOpt - Individualized model-based managing of the next-cycle thrombopenia of CHOEP/CHOP treated patients based on platelets dynamics during the previous cycles, e:Med, Genetical Statistics and Systems Biology, Task Force COVID-19 Leipzig, NFDI4Health
Institutions: Institute for Medical Informatics, Statistics and Epidemiology (IMISE)
Markus Scholz Scientific Speaker Institution Institut für Medizinische Informatik, Statistik und Epidemiologie Universität Leipzig Härtelstraße 16-18 04107 Leipzig
Projects: LIFE Heart, LIFE - Leipzig Research Center for Civilization Diseases, LIFE HNC - Head and Neck Cancer Group, SepNet - German Competence Network Sepsis, GC-HNPCC - German Consortium for Hereditary Non-Polyposis Colorectal Cancer, LIFE Child, GC-HBOC - German Consortium for Hereditary Breast and Ovarian Cancer, LIFE Adult
Web page: https://www.uniklinikum-leipzig.de/einrichtungen/life