VISEP trial data
The role of intensive insulin therapy in patients with severe sepsis is uncertain. Fluid resuscitation improves survival among patients with septic shock, but evidence is lacking to support the choice of either crystalloids or colloids. We compared intensive insulin therapy with conventional insulin therapy and HES with Ringer’s lactate.
Baseline Data and Endpoints for VISEP
LHA ID: 7WGHHJWNFX-6
Experimental assay
Projects: SepNet - German Competence Network Sepsis
Investigation: Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)
Study: VISEP
Assay position:
Resource type: Experimental Assay Type
Technology type: Technology Type
Human Diseases: disease by infectious agent
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Created: 20th May 2019 at 13:16
Last updated: 30th Aug 2019 at 13:30
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As an interdisciplinary network of scientists, the SepNet study group deals with the topics of severe sepsis and septic shock. The aim of the network is to create the prerequisites for better clinical and experimental research into sepsis and thus to develop efficient treatment approaches.
Programme: LIFE Management Cluster
Public web page: https://www.sepsis-stiftung.eu/sepnet/
Start date: 1st Jan 2003
Severe sepsis and septic shock have a high mortality. Research has concentrated on adjunctive sepsis therapies; the role of supportive measures is comparatively unclear. In Europe the use of colloids is widespread, but there is no evidence on the role of either crystalloid or colloid volume therapy in sepsis. Recently, a higher incidence of kidney failure in sepsis was reported after administration of colloids.
Baseline Data and Endpoints for VISEP
Submitter: René Hänsel
Investigation: Efficacy of Volume Substitution and Insulin The...
Resources: VISEP metadata, VISEP trial data
Study type: Not specified
Creator: Markus Löffler
Submitter: René Hänsel
Data file type: Clinical Data
Relationship type: Not specified
Creator: Markus Löffler
Submitter: René Hänsel
Data file type: ODM Data
Relationship type: Not specified
Creator: Markus Löffler
Submitter: René Hänsel
Data file type: Clinical Data
Relationship type: Not specified
Creator: Markus Löffler
Submitter: René Hänsel
Data file type: Clinical Data
Relationship type: Not specified
Creator: Markus Löffler
Submitter: René Hänsel
Data file type: Clinical Data
Relationship type: Not specified
Creator: Markus Löffler
Submitter: René Hänsel
Data file type: ODM Data
Relationship type: Not specified
Creator: Markus Löffler
Submitter: René Hänsel
Data file type: Clinical Data
Relationship type: Not specified
Creator: Markus Löffler
Submitter: René Hänsel
Data file type: ODM Data
Relationship type: Not specified
Creator: Markus Löffler
Submitter: René Hänsel
Data file type: Clinical Data
Relationship type: Not specified
Creator: Markus Löffler
Submitter: René Hänsel
Data file type: Clinical Data
Relationship type: Not specified
Projects: LHA - Leipzig Health Atlas, LIFE Adult, LIFE - Leipzig Research Center for Civilization Diseases, LIFE HNC - Head and Neck Cancer Group, LIFE Heart, MMML - Molecular mechanisms in malignant lymphoma, GLA - German Lymphoma Alliance, MMML Demonstrators - Molecular Mechanisms in Malignant Lymphomas - Demonstrators of Personalized Medicine, HaematoOpt - Individualized model-based managing of the next-cycle thrombopenia of CHOEP/CHOP treated patients based on platelets dynamics during the previous cycles, e:Med, GC-HBOC - German Consortium for Hereditary Breast and Ovarian Cancer, GC-HNPCC - German Consortium for Hereditary Non-Polyposis Colorectal Cancer, MMML-MYC-SYS, NLP4CR - Natural Language Processing for Clinical Research, Genetical Statistics and Systems Biology, SepNet - German Competence Network Sepsis, LIFE Child, HNPCC-Sys - Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome, GGN - German Glioma Network, CAPSys - Footprints of Sepsis Framed Within Community Acquired Pneumonia in the Blood Transcriptome, CapSys - Systems Medicine of Community Acquired Pneumonia, ProstataCA, HaematoSys - Systems biology of haematopoiesis and haematopoietic neoplasia, SMITH - Smart Medical Information Technology for Healthcare, Task Force COVID-19 Leipzig, NFDI4Health, POLAR - Polypharmacy, Drug Interactions, Risks, Management of health information systems, LivSys Transfer - Transfer of the LivSys in vitro system for hepatotoxicity into application, Project Test Demonstrator, Fundus photography as tool for analysis of eyes of subjects with diabetes, Clinical Trials Leipzig, NFDI4Health - TA3 Services, STOP-NUC, SCALE-TORT, EarlyAMDRate
Institutions: Institute for Medical Informatics, Statistics and Epidemiology (IMISE)
https://orcid.org/0000-0001-8344-0658
Projects: LHA - Leipzig Health Atlas, LIFE Adult, LIFE - Leipzig Research Center for Civilization Diseases, LIFE HNC - Head and Neck Cancer Group, MMML - Molecular mechanisms in malignant lymphoma, GLA - German Lymphoma Alliance, MMML Demonstrators - Molecular Mechanisms in Malignant Lymphomas - Demonstrators of Personalized Medicine, MMML-MYC-SYS, Genetical Statistics and Systems Biology, SepNet - German Competence Network Sepsis, HaematoSys - Systems biology of haematopoiesis and haematopoietic neoplasia, e:Med, SMITH - Smart Medical Information Technology for Healthcare, Task Force COVID-19 Leipzig, NFDI4Health, POLAR - Polypharmacy, Drug Interactions, Risks
Institutions: Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig
Prof. Dr. Markus Löffler Universität Leipzig Institut für Medizinische Informatik, Statistik und Epidemiologie Härtelstraße 16-18 04107 Leipzig
Projects: LIFE Heart, LIFE - Leipzig Research Center for Civilization Diseases, LIFE HNC - Head and Neck Cancer Group, SepNet - German Competence Network Sepsis, GC-HNPCC - German Consortium for Hereditary Non-Polyposis Colorectal Cancer, LIFE Child, GC-HBOC - German Consortium for Hereditary Breast and Ovarian Cancer, LIFE Adult
Web page: https://www.uniklinikum-leipzig.de/einrichtungen/life
Taxonomy URI: http://purl.obolibrary.org/obo/DOID_0050117
Synonyms: infectious disease
Definitions: A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions.
