Gene expression patterns and TP53 mutations are associated with HPV RNA status, lymph node metastasis, and survival in head and neck cancer (clinical Dataset) Version 2
ExploreOur first objective was to compare the molecular features of subgroups of HNSCC defined by their HPV16 DNA and RNA status. The second objective was to identify gene expression subtypes in HNSCC and to correlate them with other characteristics of the patients.
HPV DNA and RNA status, mutations of 50 genes, survival and other clinical characteristics of 270 patients with head and neck cancer.
LHA ID: 7WDT0T5K2X-5
Filename:
GSE65858_clinical_data.tsv
Format: Tab-separated values document
Size: 104 KB
Data file type: Clinical Data
Human Diseases: Head and neck squamous cell carcinoma
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Created: 13th May 2019 at 14:09
Last updated: 4th Dec 2019 at 11:55
Last used: 30th Dec 2024 at 16:37
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Version 2 (latest) Created 4th Dec 2019 at 11:55 by Christoph Beger
replaced archive with plain TSV file
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The aim of the Head and Neck Group within the Leipzig Research Center for Civilization Diseases (LIFE) is to facilitate improvements in the treatment and care of head and neck cancer patients through insights from molecular studies.
The Head and Neck Group within the Leipzig Research Center for Civilization Diseases (LIFE) investigates the molecular mechanisms and the diagnostic and prognostic factors of head and neck cancer. For this purpose, we collected phenotypic information from about 300 ...
Programme: LIFE Management Cluster
Public web page: http://life.uni-leipzig.de/
Start date: 1st Jan 2012
End date: 31st Dec 2012
Goal of the Leipzig Research Center for Civilization Diseases (LIFE) is the investigation of civilization diseases like depression, diabetes, allergies or cardiovascular diseases. For this purpose we collect as much data as possible regarding health and living conditions of the population in Leipzig and provide these data for scientists of the University of Leipzig and other research institutions.
Programme: LIFE Management Cluster
Public web page: http://life.uni-leipzig.de/
Start date: 1st Jan 2009
Stratification of head and neck squamous cell carcinomas (HNSCC) based on HPV16 DNA and RNA status
Stratification of head and neck squamous cell carcinomas (HNSCC) based on HPV16 DNA and RNA status
Submitter: René Hänsel
Investigation: head and neck squamous cell carcinomas
Resources: HNSCC Clinical Dataset, HNSCC OMICS Data
Study type: Clinical study (Phase 1)
Submitter: René Hänsel
Resource type: Experimental Assay Type
Technology type: Technology Type
Investigation: head and neck squamous cell carcinomas
Study: HNSCC
Abstract (Expand)
Authors: G. Wichmann, M. Rosolowski, K. Krohn, M. Kreuz, A. Boehm, A. Reiche, U. Scharrer, D. Halama, J. Bertolini, U. Bauer, D. Holzinger, M. Pawlita, J. Hess, C. Engel, D. Hasenclever, M. Scholz, P. Ahnert, H. Kirsten, A. Hemprich, C. Wittekind, O. Herbarth, F. Horn, A. Dietz, M. Loeffler
Projects: LHA - Leipzig Health Atlas, Onto-Med Research Group, SMITH - Smart Medical Information Technology for Healthcare, Task Force COVID-19 Leipzig, NFDI4Health, LIFE Child, LIFE - Leipzig Research Center for Civilization Diseases, Project Test Demonstrator
Institutions: Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Universitätsklinikum Leipzig, AöR, invalid
https://orcid.org/0000-0002-1166-0368
Profile image source: Swen Reichhold
Projects: LIFE Heart, LIFE - Leipzig Research Center for Civilization Diseases, LIFE HNC - Head and Neck Cancer Group, SepNet - German Competence Network Sepsis, GC-HNPCC - German Consortium for Hereditary Non-Polyposis Colorectal Cancer, LIFE Child, GC-HBOC - German Consortium for Hereditary Breast and Ovarian Cancer, LIFE Adult
Web page: https://www.uniklinikum-leipzig.de/einrichtungen/life
Taxonomy URI: http://purl.obolibrary.org/obo/DOID_5520
Synonyms: squamous cell carcinoma of the head and neck, squamous cell carcinomas of head and neck, carcinoma of the head and neck
Definitions: A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck., OMIM mapping confirmed by DO. [SN].
