Projects

The cultivated grape (Vitis vinifera) has become the world’s leading fruit crop. Grape is unique not only because it is a major global perennial crop but also for its historical and cultural connections with the development of humans. One of the main challenges for viticulture is to sustainably maintain the production of high-quality grape varieties in the face of climate change. Current models predict an increasing disease pressure for grapes, mainly because of warmer and partly drier conditions. ...

Background Single-cell RNA sequencing (scRNAseq) has been widely applied to dissect cellular heterogeneity in normal and diseased skin. Sebaceous glands, essential skin components with established functions in maintaining skin integrity and emerging roles in systemic energy metabolism, have been largely neglected in scRNAseq studies. Methods Departing from mouse and human skin scRNAseq datasets, we identified gene sets expressed especially in sebaceous glands with the open-source R-package oposSOM. ...

Mice RPKM count data as applied in oposSOM. The gene cluster A-H introduced in this publication.

The Leipzig Health Atlas (LHA) is an alliance of medical ontologists, medical systems biologists and clinical trials groups to design and implement a multi-functional and quality-assured atlas. It provides models, data and metadata on specific use cases from medical research fields in which our team has scientific and clinical expertise.

This project serves as a container for all COVID-19 related assets, developed at the University of Leipzig and its partners.

During 2004 and 2012 the german cancer aid supported the german glioma network (GGN). The GGN is a consortium where university hospitals with clinical focus in neuro-oncology, reference centers for neuroradiology, neuropathology, molecular diagnostics and biometry cooperate. Thanks to the long-term support it was possible to build a network of competence centers for the treatment of brain tumors in Germany wich is characterized by a interdisciplinary collaboration of all specialist disciplines ...