Studies

Medizinische Daten sind im Allgemeinen in dem Informationssystem gespeichert, welches die primäre Erfassung übernimmt. Sie befinden sich in einer Datenbank und können ggf. exportiert werden. Für eine übergreifende Nutzung haben sich Common Data Models wie OMOP oder HL7 FHIR etabliert. Ziel der Übung ist es, die Studierenden mit dem Prozess und den Schwierigkeiten der Überführung eines lokalen Datenkörpers in HL7 FHIR vertraut zu machen. Darunter fallen Fragen der Abbildung und Transformation der ...

Ziel der Übung ist es, Studierende mit der Notwendigkeit der Nutzung medizinischer Terminologien vertraut zu machen und ihnen gleichzeitig die Problematik der Annotierung von Datenelementen aus Erhebungen mit Konzepten aus internationalen Wissensbasen wie bspw. LOINC oder SNOMED CT zu verdeutlichen. Dies umfasst den Vorgang der eigentlichen Kodierung, das Finden eines passenden Codes, die Navigation in der Hierarchie der Terminologie, die Festlegung der Güte des Mappings oder die Konfidenz des ...

Recruitment of patients with idiopathic and different forms of monogenic PD, as well as healthy controls, took place at the Institute of Neurogenetics at the University of Lübeck (UL) and the Department of Neurology at the University College London (UCL). Large-scale blood based targeted metabolomics analyses of 304 metabolites covering acylcarnitines, amines, organic acids, lipids and signaling lipids were performed in 140 idiopathic and 19 monogenic PD patients and 64 controls.

A meta-analysis of genome-wide associations for serum vaspin from six independent cohorts (N = 7446) was conducted. The data show that serum vaspin is strongly determined by genetic variants within vaspin.

This study belongs to the publication: https://doi.org/10.1002/oby.23882

The test data

• are freely invented by clinical experts (manually, synthetically) and have no relation to real persons
• have been generated by a tool developed at the University of Leipzig from contributions of different expert groups out of a MS Excel format
• are available for free use as HL7® FHIR® bundles in json format;
• are suitable for direct transfer into a FHIR server
• correspond as far as ...

A collection of Bulletins of the Institute for Medical Informatics, Statistics and Epidemiology (IMISE) about the COVID-19 pandemic in Leipzig and Saxony. This work was funded in the framework of the project SaxoCOV (Saxonian COVID-19 Research Consortium, SaxoCOV was financed by the Free State of Saxony).”

To achieve the objective of Use Case 1, a retrospective study has been performed with data from 5 EU cohorts in different health care settings (hospital, primary care, nursing homes) and health research organizations:

1. UNIGE: provides anonymized health care data from the EHR of the University Hospitals of Geneva.
2. SAS: provides health care data from the EHR of the Virgen del Rocío University Hospital in Seville as part of the Andalusian Health Service.
3. UCSC: provides health ...