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28 Data files visible to you, out of a total of 31
No description specified

Creators: Alexandr Uciteli, Christoph Beger, Toralf Kirsten, Heinrich Herre, Franz Matthies, Ralph Schäfermeier

Submitter: Christoph Beger

Data file type: Not specified

Human Diseases: obesity, hypertension

We performed gene-expression profiling using Affymetrix U133A GeneChips with RNA from 220 mature aggressive B-cell lymphomas, including a core group of 8 Burkitt's lymphomas that met all World Health Organization (WHO) criteria. A molecular signature for Burkitt's lymphoma was generated, and chromosomal abnormalities were detected with interphase fluorescence in situ hybridization and array-based comparative genomic hybridization.

Creator: Michael Hummel

Submitter: Christoph Beger

Data file type: Genomic Data

Human Diseases: B-cell lymphoma

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed microarray-based genome- and transcriptome-wide molecular profiling of primary tumor samples from 137 patients with cerebral gliomas, 61 WHO grade II and 76 WHO grade III tumors.

Creators: Henry Löffler-Wirth, Markus Kreuz

Submitter: Christoph Beger

Data file type: Genomic Data

Human Diseases: brain glioma

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed Methylation profiling of primary tumor samples from 122 patients with cerebral gliomas with WHO grade II and grade III tumors.

Creators: Hans Binder, Markus Kreuz, Henry Löffler-Wirth

Submitter: Christoph Beger

Data file type: Methylation Data

Human Diseases: brain glioma

No description specified

Creator: Matthias Löbe

Submitter: Christoph Beger

Data file type: Not specified

Based on the assumption that molecular mechanisms involved in cancerogenesis are characterized by groups of coordinately expressed genes, we developed and validated a novel method for analyzing transcriptional data called Correlated Gene Set Analysis (CGSA). Using 50 extracted gene sets we identified three different profiles of tumors in a cohort of 364 Diffuse large B-cell (DLBCL) and related mature aggressive B-cell lymphomas other than Burkitt lymphoma. The first profile had high level of ...

Creator: Maciej Rosolowski

Submitter: Christoph Beger

Data file type: Transcriptomic Data

Human Diseases: diffuse large B-cell lymphoma

307 single cells cultured from three biopsies of three different patients with a BRAF/NRAS wild type, BRAF mutant/NRAS wild type and BRAF wild type/NRAS mutant melanoma metastasis, respectively

Creators: Hans Binder, Henry Löffler-Wirth, Manfred Kunz

Submitter: Christoph Beger

Data file type: Genomic Data

Human Diseases: melanoma

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