GC-HBOC Mutation Frequency Explorer
Version 1

Motivation: The "GC-HBOC Mutation Frequency Explorer" can be used to assist clinicians and genetic counselors in the clinical management of families suspected of having hereditary breast and ovarian cancer and to decide whether genetic testing should be performed.

Description: The "GC-HBOC Mutation Frequency Explorer" is a tool to determine the observed frequencies of pathogenic BRCA1 and BRCA2 mutations based on familial cancer history data collected since 1996 by the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) in over 36,000 families suspected of having hereditary breast and ovarian cancer (Kast et al, 2016). This tool allows querying mutation frequencies for both predefined as well as flexibly customizable familial cancer histories.


1 item is associated with this Model:

Human Disease: Hereditary breast ovarian cancer syndrome

Model type: Not specified

Model format: R package

Execution or visualisation environment: Shiny

Model image: No image specified

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Views: 2905

Created: 1st Apr 2019 at 10:34

Last updated: 8th Jul 2019 at 10:16

Last used: 2nd Jun 2023 at 19:04

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Version History

Version 1 Created 1st Apr 2019 at 10:34 by Silke Zachariae

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