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Diabetes screening strategies using glycated haemoglobin (HbA1c) as first-instance diagnostic parameter may cause failure to detect individuals with abnormal glucose regulation and possible signs of microvascular complications despite “rule-out” HbA1c levels. This cross-sectional study examined the diagnostic performance of HbA1c in relation to fasting and two-hour postload plasma glucose (FPG/2 h-PG), and investigated whether individuals with normal HbA1c but abnormal FPG/2 h-PG have a higher ...

Introduction The platform can be found at the following address: https://apps.health-atlas.de/hemato-models/ This platform enables data fitting, results presentation and next cycle prediction/management using hematopoietic models, developed by our modeling group in IMISE: a) Erythropoiesis model b) Individualised thrombopoiesis model [1] integrated with a model of bone-remodelling [2] as well as with PK models of few cytotoxic drugs [3,4] c) Integral hemathopoiesis model (above thrombopoiesis ...

Background: Covid-19 pandemic is developing worldwide with common dynamics but also with partly marked differences between regions and countries. They are not completely understood, but presumably, provide one clue to find ways to mitigate epidemics until exit strategies to its eradication become available. Method: We provide a monitoring tool available at www.izbi.de. It enables inspection of the dynamic state of the epidemic in 187 countries using trajectories. They visualize transmission and ...

The publication of research results is part of good scientific practice and is increasingly ex-pected and demanded. The FAIR data principles of data sharing are an important guideline - even if medical data sharing makes it necessary to define access restrictions.