LHA ID: 8V6T33PCAE-7
Location:
Germany
ORCID:
https://orcid.org/0000-0002-5735-0197
Joined: 8th May 2025
Expertise: Not specified
Tools: Not specified
Related items
The software components and the interim results of the project's article by Wermund et al. (2025; https://doi.org/10.1371/journal.pdig.0000892) are available under "Related Items" > "Models".
Programme: MII - Medical Informatics Initiative
Public web page: https://www.medizininformatik-initiative.de/en/POLAR
Organisms: Not specified
The aim of the project is to use methods and processes of the Medical Informatics Initiative (MII) to contribute to the detection of health risks in patients with polypharmacy. Polypharmacy occurs especially in elderly patients with multimorbidity. Polypharmacy associated with an increased risk for medication errors and drug-drug or drug-disease interactions, which either reduce or intensify the desired effect of individual active substances or lead to undesired adverse drug effects (ADE). In the ...
Programme: MII - Medical Informatics Initiative
Public web page: https://www.medizininformatik-initiative.de/en/POLAR
Organisms: Homo sapiens
The interim results are the results from the local statistical analysis at each centre, which were subsequently pooled in the mixed effects meta-analysis.
Note, that the centres are pseudonymised. Interim results are provided for the subset of centres (out of ten), who provided their consent for sharing the results as they were used for the meta-analysis. The pseudonymised names are those that are mentioned in some of the text files for the meta-analysis.
The folder suffix identifies whether ...
Creator: Anna Wermund
Submitter: Anna Wermund
Model type: Not specified
Model format: Not specified
Environment: Not specified
Organism: Not specified
Human Disease: Not specified
Investigations: No Investigations
Studies: No Studies
Resources: No Resources
The provided software provides the R modules for both parts of the applied POLAR_MI ETL Pipeline, the distributed analysis approach developed within POLAR_MI:
- Part 1: local data retrieval (WP_1_5_local_DataRetrieval.zip) and local statistical analysis (WP_1_5_local_StatisticalAnalysis.zip) for local execution at each centre
- Part 2: meta-analysis of local results (interim results; WP_1_5_central_Metaanalysis.zip)
Within compressed folder, we provide “read me” files with further information.
Creator: Anna Wermund
Submitter: Anna Wermund
Model type: Not specified
Model format: R package
Environment: RStudio
Organism: Not specified
Human Disease: Not specified
Investigations: No Investigations
Studies: No Studies
Resources: No Resources
The medical informatics initiative was created to close the gap between research and healthcare. All of Germany’s university hospitals have joined forces with research institutions, businesses, health insurers, and patient advocacy groups to create a framework that harnesses research findings to the direct benefit of patients. The German Federal Ministry of Education and Research (BMBF) is investing around 160 million euros in the programme through 2021. The digitisation of medicine is creating ...
Projects: Methodical Use Case PheP, SMITH - Smart Medical Information Technology for Healthcare, WP 1.5 of POLAR_MI (Polypharmacy, Drug Interactions, Risks) - Development of risk models, POLAR - Polypharmacy, Drug Interactions, Risks
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