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Single-cell transcriptomics has been used for analysis of heterogeneous populations of cells during developmental processes and for analysis of tumor cell heterogeneity. More recently, analysis of pseudotime (PT) dynamics of heterogeneous cell populations has been established as a powerful concept to study developmental processes. Here we perform PT analysis of 3 melanoma short-term cultures with different genetic backgrounds to study specific and concordant properties of PT dynamics of selected ...

Creator: Henry Löffler-Wirth

Submitters: Henry Löffler-Wirth, René Hänsel

Data file type: SOM Data

For this study, we screened prospectively recruited patients with a histopathological reference diagnosis of cerebral tumors of WHO grade II and III, known KPS at diagnosis, information on extent of resection by early postoperative neuroimaging, available frozen tissue specimens from the initial operation, and documented clinical outcome.

Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological ...

Creator: Henry Löffler-Wirth

Submitters: Henry Löffler-Wirth, René Hänsel

Data file type: SOM Data

ROIs of size 600 x 900 px (0.109 mm^2) size were chosen from 25 expert-specified tumor subregions within DLBCL biopsy specimens. Images were generated by Hamamatsu Nanozoomer 2.0 RS slide scanner. ROI no. 1 - 25 represent staining with CD14 antibody (imaged at 488 nm wavelength), ROI no. 26 -- 50 represent staining with CD163 antibody (imaged at 555 nm wavelength). Imaged regions in ROIs no. 1 and 26, 2 and 27, ... , coincide. Data were used for mutual comparison of automated macrophage recognition ...

Creators: Marcus Wagner, René Hänsel

Submitter: René Hänsel

Data file type: Image Data

No description specified

Creator: Janne Pott

Submitter: René Hänsel

Data file type: Clinical Data

No description specified

Creator: Marita Ziepert

Submitter: René Hänsel

Data file type: Clinical Data

No description specified

Creator: Christoph Engel

Submitter: René Hänsel

Data file type: Clinical Data

No description specified

Creator: Christoph Engel

Submitters: Marita Ziepert, Christoph Beger

Data file type: ODM Data

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