1 item tagged with 'colorectal cancer'.
Colorectal cancer (CRC) arising in Lynch syndrome (LS) comprises tumours with constitutional mutations in DNA mismatch repair genes. There is still a lack of whole-genome and transcriptome studies of LS-CRC to address questions about similarities and differences in mutation and gene expression characteristics between LS-CRC and sporadic CRC, about the molecular heterogeneity of LS-CRC, and about specific mechanisms of LS-CRC genesis linked to dysfunctional mismatch repair in LS colonic mucosa and ...
Creator: Hans Binder
Submitter: Henry Löffler-Wirth
Data file type: SOM Data
Human Diseases: Lynch syndrome
Investigations: No Investigations
Studies: No Studies
Resources: No Resources
Created: 20th May 2019 at 13:20, Last updated: 20th May 2019 at 13:20