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65 Publications visible to you, out of a total of 65
Consolidation radiotherapy to bulky disease in aggressive NHL. First results of the NHL B-94 trial of the DSHNHL.
GLA - German Lymphoma Alliance

Abstract (Expand)

The impact of radiotherapy in aggressive NHL is not well defined. In the NHL B-94 trial of the DSHNHL, an irradiation of bulky disease areas was done after completing 6 cycles of CHOP/CHOEP chemotherapy. … In the entire patient group, including those patients with extranodal disease and those who did not receive the complete chemotherapy, bulky disease was a significant independent prognostic factor concerning recurrence-free survival (66.1% (no bulk) vs. 53.3% (bulk), p=0.0001). Out of 366 patients with nodal disease only and 6 cycles of chemotherapy according to the protocol, 84 of 91 patients with bulky disease were irradiated with 36 Gy. In this group of patients the prognostic impact of bulky disease could not be shown any longer (recurrence-free survival 77.3% (no bulk) vs. 74.1% (bulk). Localized radiotherapy of bulky disease areas may therefore have contributed to an improvement in outcome in this high-risk group.

Authors: C. Rube, T. P. Nguyen, M. Kloss, M. Loeffler, L. Trumper, M. Pfreunschuh

Date Published: 5th Jan 2002

Publication Type: Not specified

Human Diseases: non-Hodgkin lymphoma

Potential of chromosomal and matrix-based comparative genomic hybridization for molecular diagnostics in lymphomas.
GLA - German Lymphoma Alliance

Abstract

Not specified

Authors: S. Wessendorf, P. Lichter, C. Schwanen, B. Fritz, M. Baudis, K. Walenta, M. Kloess, H. Dohner, M. Bentz

Date Published: 5th Jan 2002

Publication Type: Not specified

Human Diseases: lymphoma

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