PEGFILGRASTIM PEGFILGRASTIM PEGFILGRASTIM years months Patient identification number within trial Therapy arm Gender Age (years) IPI factor age>60 years IPI factor LDH>N IPI factor ECOG>1 IPI factor stage III/IV IPI factor extralymphatic involvement > 1 IPI score Extralymphatic involvement Bulky disease B-symptoms Bone marrow involvement Reference pathology diagnosis Event-free survival (months) Event-free survival status Progression-free survival (months) Progression-free survival status Overall survival (months) Overall survival status 6 x CHOP-14 + PEG d2 6 x CHOP-14 + PEG d4 6 x CHOP-14 + 8xR + PEG d2 6 x CHOP-14 + 8xR + PEG d4 8 x CHOP-14 + PEG d2 8 x CHOP-14 + PEG d4 8 x CHOP-14 + 8xR + PEG d2 8 x CHOP-14 + 8xR + PEG d4 male female age <= 60 years age > 60 years LDH <= N LDH > N ECOG <= 1 ECOG > 1 stage I/ II stage III/ IV E <= 1 E > 1 no yes no yes no yes no yes 1040 1044 1080 1090 1035 1036 1050 1100 1000 3040 censored event censored event censored event